Microglia as modulators of cognition and neuropsychiatric disorders

Gut Microbiota and Neuropsychiatric Disorders

Special Issue: Cognition in Neuropsychiatric Disorders Computational psychiatry

P. Read Montague, Raymond J. Dolan, Karl J. Friston and Peter Dayan 1 Virginia Tech Carilion Research Institute and Department of Physics, Virginia Tech, 2 Riverside Circle, Roanoke, VA 24016, USA 2 Wellcome Trust Centre for Neuroimaging, University College London, 12 Queen Square, London, WC1N 3BG, UK 3 Gatsby Computational Neuroscience Unit, Alexandra House, 17 Queen Square, London, WC1N 3AR, UK

Nutritional Modulators of Neuropsychiatric Dysfunction

This review article gathers evidence on the potential relationship between dietary intake of 3 polyunsaturated fatty acids ( 3 PUFAs) and mental function. Several pieces of evidence that 3 PUFAs influence affective and cognitive function are presented. Although published data and results available in the field remain limited and sometimes ambiguous, they have shed a new light on the role of pro...

Can noninvasive brain stimulation enhance cognition in neuropsychiatric disorders?

Cognitive impairment is a core symptom of many neuropsychiatric diseases and a key contributor to the patient's quality of life. However, an effective therapeutic strategy has yet to be developed. Noninvasive brain stimulation techniques, namely transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), are promising techniques that are under investigation for a...

Nutritional and Nanotechnological Modulators of Microglia

Microglia are the essential responders to alimentary, pharmacological, and nanotechnological immunomodulators. These neural cells play multiple roles as surveyors, sculptors, and guardians of essential parts of complex neural circuitries. Microglia can play dual roles in the central nervous system; they can be deleterious and/or protective. The immunomodulatory effects of alimentary components,...